Metformin mimics several pathways associated with caloric restriction and fasting. The body perceives these interventions as stressors and then adapts, ultimately developing metabolic flexibility. Dr. D’Agostino proposes that metabolic interventions, such as restricting calories and entering ketosis, for example, may provide additional benefits when practiced cyclically. In this clip, Dr. Dominic D’Agostino explains how the periodic use of fasting and associated practices may provide health benefits.
This clip was taken from the first FoundMyFitness interview with Dominic D’Agostino found at https://www.youtube.com/watch?v=lQ7pSXIWHrI
Original episode published on Apr 9, 2016
#metformin #caloricrestriction #fasting